Extreme Hyperlipasemia in Acute Pancreatitis with Rapid Clinical and Biochemical Recovery: A Case Report
SM Raju
ABSTRACT
Background: Acute pancreatitis is an inflammatory condition of the pancreas characterized by severe abdominal pain and elevation of pancreatic enzymes. Management is largely supportive, and recovery in moderate to severe cases may be prolonged, with delayed normalization of biochemical markers. Rapid clinical and laboratory recovery is uncommon in cases presenting with markedly elevated enzyme levels.
Case Presentation: A 32-year-old male presented with persistent severe upper abdominal pain lasting nearly 20 days. Laboratory evaluation revealed markedly elevated pancreatic enzymes, with serum lipase at 3531 U/L and serum amylase at 1710 U/L, indicating severe acute pancreatic inflammation. A structured integrative intervention was initiated, consisting of a defined herbal formulation protocol administered in three daily doses along with a lowinflammatory, renal-supportive dietary regimen aimed at reducing digestive workload and supporting systemic metabolic balance.
Outcome: Within 72 hours of initiating treatment, the patient reported significant reduction in abdominal pain, with near-complete relief by the third day. Follow-up laboratory testing performed 10 days after treatment initiation demonstrated rapid biochemical improvement, with serum lipase decreasing to 98.8 U/L and serum amylase to 98.1 U/L, both within near-normal range. The patient resumed normal daily activities and remained symptom-free at follow-up.
Conclusion: This case demonstrates unusually rapid clinical and biochemical recovery in severe acute pancreatitis. The findings suggest that structured integrative supportive approaches may contribute to accelerated recovery and merit further systematic clinical investigation.
