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ISSN: 2755-6328 | Open Access

Open Access Journal of Pharmaceutical Sciences and Drugs

Volume : 1 Issue : 2

Full Recovery from Chronic Fatigue Caused by Reactivation of the Epstein Barr Virus Through the Use of Basic Micronutrition and Specific Micronutrition 

Flores Montero Natalia*, Blanco Rogel Mar and Capdevila Menac Núria

ABSTRACT
Background and Objective:
Chronic fatigue syndrome (CFS) is a disorder whose main symptom is tiredness that fails to improve with rest and worsens with exercise. It is a complex and chronic disorder of unknown etiology with general, physical and neurophysical manifestations.

There are numerous theories regarding its etiology. Prominent among them are problems related to mitochondrial bioenergetic functioning and latent infections with the Epstein-Barr virus (EBV) and cytomegalovirus (CMV). The objective of this case was to address the intense fatigue caused by EBV and CMV.

Method and Results: Man, 43 years of age, suffering from incapacitating CFS since 2016 and with a prior history of immune dysfunction in the form of recurrent tonsillitis and infectious mononucleosis. Viral serology testing detects reactivation of the EBV and elevated CMV and IgG.

A diet free of gluten, dairy products, and saturated fats is prescribed. At the same time escitalopram is discontinued, his lorazepam dose is lowered, and supplementation with micronutrients, probiotics, micotherapy, and micro-immunotherapy is started. In the first and second control visit (3.5 months), different adjustments are made in response to the improvement in the fatigue and clinical symptoms. After three months (third visit), specific micronutrients aimed at stimulating mitochondrial metabolism and increasing NAD+ are given. Three months later, in the last visit, he reports a spectacular change in his energy level compatible with family and work life, restful sleep, and satisfactory physical activity.

Conclusion: The increased NAD+ levels and supplementation with micronutrients that play a part in biochemistry and mitochondrial dynamics were essential factors in recovery from the intense fatigue and improvement of the mitochondrial machinery related to the immune response.

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